ANKMJ

Ankyra Medical Journal (AnkMJ), formerly known as the Journal of Translational and Practical Medicine, regularly publishes international quality issues in the field of Medicine in the light of current information.

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Case Report
Papillon-Lefèvre syndrome in early childhood: a case report with literature review
Papillon-Lefèvre syndrome (PLS) is a rare genetic disorder with autosomal recessive inheritance, typically manifesting in childhood. The hallmark features include palmoplantar hyperkeratosis and premature loss of teeth. Additional associated findings may include psoriasiform plaques on the knees and elbows, hyperhidrosis, recurrent pyogenic infections, intracranial calcifications, and both physical and mental developmental delays. This case report presents a 5-year-old child who was admitted to the Faculty of Dentistry at Kırıkkale University with tooth loss and was subsequently diagnosed with Papillon-Lefèvre Syndrome, accompanied by a review of the relevant literature.


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Volume 5, Issue 1, 2026
Page : 24-28
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