ANKMJ
Ankyra Medical Journal

Ankyra Medical Journal (AnkMJ), formerly known as the Journal of Translational and Practical Medicine, regularly publishes international quality issues in the field of Medicine in the light of current information.

eISSN: 3023-655X
Creative Commons CC BY-NC-ND 4.0 International License.
EndNote Style

Online Manuscript System

Index
Review
Principles of the diuretic using
Abstract
Water and electrolyte balances are essential in the body. Many conditions, especially heart and kidney failure, venous insufficiency, and drugs, cause edema. In these patients, the diagnosis of edema, the evaluation of the patient in terms of critical underlying pathologies, and appropriate treatment are essential. The use of diuretics in conditions related to the disease is essential for both the treatment of edema and the clinical relief of the patient. Diuretic doses are ineffective or may cause problems due to excessive diuresis when diuretic doses are not appropriately adjusted. This review emphasizes the principles of diuretic use and essential points to be considered.

Keywords : Diuretics, diuretic using, edema

Download Article


1. Tobias A, Ballard BD, Mohiuddin SS. Physiology, Water Balance. [Updated 2021 Oct 9]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK541059/
2. Ellison DH. Clinical pharmacology in diuretic use. Clin J Am Soc Nephrol 2019; 14: 1248-57.
3. Brater DC. Diuretic therapy. N Engl J Med 1998; 339; 387-95.
4. Kıykım AA, Çamsarı A. Ödemli hastalarda diüretik kullanımı. Anadolu Kardiyol Derg 2003; 3: 65-70.
5. Felker GM, Ellison DH, Mullens W , Cox ZL, Testani JM. Diuretic therapy for patients with heart failure: JACC state-of-the-art review. J Am Coll Cardiol 2020; 5: 1178-95.
6. Greenberg A. Diuretic complications. Am J Med Sci 2000; 319: 10-24.
7. UpToDate. Pathophysiology and etiology of edema in adults. https://www.uptodate.com/contents/pathophysiology-and-etiology-of-edema-in-adults
8. O'Brien JG, Chennubhotla SA, Chennubhotla RV. Treatment of edema. Am Fam Physician. 2005; 71: 2111-7.
9. Oh SW, Han SY. Loop diuretics in clinical practice. Electrolyte Blood Press 2015; 13: 17-21.
10. UpToDate. Mechanism of action of diuretics. https://www.uptodate.com/contents/mechanism-of-action-of-diuretics
11. Sanofi. Lasix 40 mg tablet. https://www.sanofi.com.tr/dam/jcr:6857f98f-b29b-49b8-bc70-d6c446fed8f8/Lasix-40-mg-kub.pdf
12. van Olden RW , van Meyel JJW , Gerlag PGG. Sensitivity of residual nephrons to high dose furosemid described by diuretic efficiency. Eur J Clin Pharmacol 1995; 47: 483-8.
13. Ochs HR, Greenblatt DJ, Bodem G, Smith TW. Spironolactone. American Heart J 1978; 96: 389-400.
14. Zannad F, McMurray JJ, Krum H, et al. Eplerenone in patients with systolic heart failure and mild symptoms. N Engl J Med 2011; 364: 11-21.
15. Shah S, Khatri I, Freis ED. Mechanism of antihypertensive effect of thiazide diuretics. Am Heart J 1978; 95: 611-8.
16. Salvetti A, Ghiadoni L. Thiazide diuretics in the treatment of hypertension: an update. J Am Soc Nephrol 2006; 17: S25-S29.
17. Farzam K, Abdullah M. Acetazolamide. StatPearls [Internet]. 2021.
18. https://www.uptodate.com/contents/complications-of-mannitol-therapy
19. Jackson AM, Dewan P , Anand IS, et al. Dapagliflozin and diuretic use in patients with heart failure and reduced ejection fraction in DAPA-HF. Circulation 2020; 142: 1040-54.
20. Griffin M, Rao VS, Ivey-Miranda J, et al. Empagliflozin in heart failure: diuretic and cardiorenal effects. Circulation 2020; 142: 1028-39.
21. Ansary TM, Nakano D, Nishiyama A. Diuretic effects of sodium glucose cotransporter 2 inhibitors and their influence on the renin-angiotensin system. Int J Molecular Sci 2019; 20: 629.
22. Kalra, S. Sodium Glucose Co-Transporter-2 (SGLT2) Inhibitors: a review of their basic and clinical pharmacology. Diabetes Ther 2014; 5: 355–66.
23. Simes BC, MacGregor GG. Sodium-Glucose Cotransporter-2 (SGLT2) Inhibitors: A Clinician's Guide. Diabetes, metabolic syndrome and obesity: targets and therapy, 2019; 12: 2125–36.
24. Vardeny O, Claggett B, Kachadourian J, et al. Reduced loop diuretic use in patients taking sacubitril/valsartan compared with enalapril: the PARADIGM-HF trial. Eur J Heart Failure 2019; 21: 337-41.
25. Hormann SM, Davis LE, Pogge EK. The diuretic potential of sacubitril/valsartan: a tale of 2 patients. J Cardiovasc Nurs 2018; 33: 104-10.
26. Hubers SA, Brown NJ. Combined Angiotensin Receptor Antagonism and Neprilysin Inhibition. Circulation 2016; 133: 1115–24.
27. Krittanawong C, Kitai T. Pharmacogenomics of angiotensin receptor/neprilysin inhibitor and its long-term side effects. Cardiovasc Therapeutics 2017; 35: e12272.
28. Trayes KP, Studdiford JS, Pickle S, taully AS. Edema: diagnosis and management. Am Fam Physician 2013: 88: 102-10.
29. Krämer BK, Schweda F, Riegger GA. Diuretic treatment and diuretic resistance in heart failure. Am J Med 1999;106: 90-96.
30. Beermann B. Aspects of some pharmacokinetics of some diuretics. Acta Pharmacol Toxicol 1984; 54: 17-29.
31. Huang CM, Atkinson Jr, AJ, Levin M, Levin NW , Quintanilla A. Pharmacokinetics of furosemide in advanced renal failure. Clin Pharmacol Therapeutics 1974; 16: 659-66.
32. Risey JA, Guth PS, Amedee RG. Furosemide distinguishes central and peripheral tinnitus. Int Tinnitus J 1995; 1: 99-103.
Article available in :
Volume 1, Issue 2, 2022
Page : 57-60
https://doi.org/10.51271/JTPM-0001
Article Information
Received : 21 Mar 2022
Accepted : 24 Tem 2022
Published : 30 Eyl 2022
Corresponding Author :

Aydın Çifci: Department of Internal Medicine, Faculty of Medicine, Kırıkkale University, Kırıkkale, Turkiye

[email protected]
Citation : Çifci A, Varlıbaş A. Principles of the diuretic using. J Transl Pract Med 2022; 1(2): 57-60.

Read: 787
Download : 537
Cited: 0
_Footer